Brisbane Clinical Trials

The Swell Study

The study drug is a potential new treatment for hereditary angioedema (HAE).

2 nights
10 visits

HAE is a rare genetic condition that causes episodes of swelling in different parts of the body, including face, hands, feet, and airway. The study drug is a subcutaneous injection that is administered into the abdomen, upper arm, or thigh. Participants will receive a single dose.

Most current treatments are focused on reducing swelling. There are also preventative treatments, but these aren’t effective for all patients, and some need to be administered frequently. There is a need for more convenient and effective treatments to prevent these swelling episodes.

The trial has been approved by an independent ethics committee and eligible participants will be reimbursed for their time.

Eligibility

Biological Sex Healthy males and females
Age 18 – 60 years old, inclusive
BMI 18 – 32 kg/m²
Weight >50kg
Medical History No significant medical history
Medication Not taking any medication
Smoking History Smoking no more than 10 cigarettes per day