The purpose is to determine the absorption and elimination rate of tolebrutinib in patient with liver disease vs normal liver function.

4 nights
3 visits

Purpose: to evaluate the safety and tolerability of an investigational medication for the treatment of multiple sclerosis in participants with mild liver cirrhosis

This study has 4 nights/ 5 day consecutive stay in-house at our St. Paul facility plus 1 outpatient visit.

This study has been approved by an independent ethics committee.

Reimbursement for study participation will be provided for time and travel of up to $1,500.

Call Tyler at 612-368-6967 or register your interest to discuss your eligibility today!

Transportation maybe arranged to and from the clinic for appointments.

Eligibility

Age: 18-79 years old
BMI: 18-40 kg/m2
Medications: Stable medications for 14 days prior to admit
Smoking Status: Nonsmoker or smoking less than 15 cigarettes per day. Able to refrain from smoking over 8 cigarettes per day during inpatient stay.
Compensation: Up to $1,500